Viral Nuclease Inhibitors: Small molecule disruptors of the UL12 alkaline nuclease display broad anti-herpes virus activity
Nidhi Sharma, Xiaoyun Xie, Renata Szczepaniak, Chitra Rani, Sheida Khojasteh Khosro, J. Krucinska, Xueao Chen, Dung Do, Lee Wright, Dennis Wright, Sandra Weller
This paper identifies small molecule inhibitors of herpesvirus alkaline nucleases that show broad antiviral activity against HSV-1 and HCMV.
PLoS Pathogens · Aug 17, 2026Peer-reviewedPharmacology & Toxicology