Hedgehog signaling activates a heterochronic gene regulatory network to control differentiation timing across lineages
Megan Rowton, Carlos Perez-Cervantes, Suzy S. J. Hur, Jessica Jacobs-Li, Emery Lu, Nikita Deng, Alexander Guzzetta, Andrew Daniel Hoffmann, Matthew Stocker, Jeffrey D. Steimle, Sonja Lazarevic, Sophie Oubaha, Xinan Holly Yang, Chul Kim, Shu‐Han Yu, , Ivan P. G. Moskowitz
This study identifies Hedgehog signaling as a regulator of differentiation timing through a heterochronic gene regulatory network in cardiac and neural lineages.
Developmental Cell · Sep 1, 2022Peer-reviewedDevelopmental Biology