Jessica Jacobs-Li

The paper uses single-cell transcriptomics and lineage tracing in avian embryos to show that sacral neural crest cells contribute to specific neurons, glia, and mesenchymal cells in the post-umbilical gut.

This study identifies Hedgehog signaling as a regulator of differentiation timing through a heterochronic gene regulatory network in cardiac and neural lineages.

This study identifies a Hedgehog-FGF signaling axis critical for anterior mesoderm patterning during gastrulation using single-cell transcriptomics in Hh-deficient embryos.