Author

Niklas Herrle

Goethe University Frankfurt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Physiology· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Approach:statistical model· 1

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Alfredo Cabrera‐OreficeiD· 1 shared Amparo Acker‐PalmeriD· 1 shared Carine KaderiD· 1 shared Ewgenij ProschakiD· 1 shared Flávia RezendeiD· 1 shared Frank Erhard UschneriD· 1 shared Ilka WittigiD· 1 shared Ina KochiD· 1 shared

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2025-2025 · peak 1/yr

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Alfredo Cabrera‐OreficeORCID

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1 paper

Recent·Most cited

The transaminase-omega-amidase pathway is a redox switch in glutamine metabolism that generates alpha-ketoglutarate

Niklas Herrle, Pedro Felipe Malacarne, Timothy Warwick, Alfredo Cabrera‐Orefice, Yiheng Chen, Maedeh Gheisari, Souradeep Chatterjee, Matthias S. Leisegang, Tamim Sarakpi, Sarah Wionski, Melina Lopez, Carine Kader, Tom Teichmann, Maria-Kyriaki Drekolia, Ina Koch, , Flávia Rezende

The paper identifies the transaminase-omega-amidase pathway as a redox-sensitive metabolic switch in endothelial glutamine metabolism, showing that NIT2 oxidation inhibits its activity and affects angiogenesis.

The EMBO Journal · Dec 17, 2025Peer-reviewedPhysiology