Frank Erhard Uschner

The transaminase-omega-amidase pathway is a redox switch in glutamine metabolism that generates alpha-ketoglutarate

The paper identifies the transaminase-omega-amidase pathway as a redox-sensitive metabolic switch in endothelial glutamine metabolism, showing that NIT2 oxidation inhibits its activity and affects angiogenesis.

Refined Enterotyping Reveals Dysbiosis in Global Fecal Metagenomes

The paper refines enterotypes in global fecal metagenomes using fuzzy clustering and introduces an Enterotype Dysbiosis Score to assess disease associations.

Dynamic human liver proteome atlas reveals functional insights into disease pathways

The paper quantifies the human liver proteome at cell-type resolution across multiple conditions, revealing proteome changes in disease states and providing a web-based resource for exploration.

Intercellular crosstalk regulating ARRB2/RARRES1 is involved in transition from fibrosis to cancer

This study identifies a molecular pathway involving ARRB2 and RARRES1 that regulates the transition from liver fibrosis to cancer, with implications for diagnostics and therapeutics.