Author

Nikolaus Grigorieff

Primary ORCID profile (0000-0002-1506-909X · 14 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Nikolaus GrigorieffiD14 papers · Howard Hughes Medical Institute

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Organism:chicken / avian· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:electronic health records· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Alexis Rohou· 2 shared Alexis Rohu· 1 shared Anna Zhou· 1 shared Daniel G Schep· 1 shared David A. AgardiD· 1 shared Elena A. Zehr· 1 shared Joe Pogliano· 1 shared John E Walker· 1 shared

Activity by Year

2015-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

Alexis Rohou

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanistic Origins of Dynamic Instability in Filaments from the Phage Tubulin, PhuZ

Elena A. Zehr, Alexis Rohu, Yanxin Liu, Kliment A. Verba, Joe Pogliano, Nikolaus Grigorieff, David A. Agard

The paper investigates how GTP binding and hydrolysis control dynamic instability in PhuZ filaments, revealing structural changes and mechanisms distinct from microtubules.

bioRxiv · Apr 30, 2018 · PreprintCell Biology

Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM

Anna Zhou, Alexis Rohou, Daniel G Schep, John V Bason, Martin G Montgomery, John E Walker, Nikolaus Grigorieff, John L Rubinstein

This study uses cryo-EM to determine the structure and conformational states of bovine mitochondrial ATP synthase, revealing proton translocation mechanisms and rotational dynamics.

bioRxiv · Oct 1, 2015Biochemistry

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

Alexis Rohou, Nikolaus Grigorieff

The paper improves CTFFIND4, a tool for estimating defocus parameters in electron micrographs, making it faster and more suitable for modern imaging techniques while maintaining accuracy.

bioRxiv · Aug 13, 2015Biophysics