LipoGrid: A High-Throughput Multi-omics Perturbation Screen Dissects the Genetic Architecture of Lipid Metabolism
Jelle Jacobs, Paulien Van Minsel, Nina Ravoet, Emiel De Rieck, Niels Vandermeulen, Lorenzo Venturelli, Katy Vandereyken, Karen Ven, Jolien Breukers, D. J. Wouters, Thierry Voet, Jeroen Lammertyn, Johannes V. Swinnen, Bernard Thienpont, Alejandro Sifrim
LipoGrid quantifies lipidomic and transcriptomic changes across 143 gene knockouts, revealing gene-lipid relationships and compensatory feedback mechanisms.
bioRxiv · Aug 17, 2026 · PreprintSystems Biology