Author

Nikshitha Tulasi

Heidelberg University

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Genetics· 1

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Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

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Axel FreischmidtiD· 1 shared Benedikt BrorsiD· 1 shared Dávid BrenneriD· 1 shared Jochen Hans WeishauptiD· 1 shared Johannes C. M. SchlachetzkiiD· 1 shared Karin ForsbergiD· 1 shared Lena Voith von VoithenbergiD· 1 shared Lorena Decker· 1 shared

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Axel FreischmidtORCID

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1 paper

Recent·Most cited

Somatic mutations in ALS genes in the motor cortex of sporadic ALS patients

Óscar González-Velasco, Rosanna Parlato, Rüstem Yilmaz, Lorena Decker, Sonja Menge, Axel Freischmidt, Xiaoxu Yang, Nikshitha Tulasi, Dávid Brenner, Peter Munch Andersen, Karin Forsberg, Johannes C. M. Schlachetzki, Benedikt Brors, Lena Voith von Voithenberg, Jochen Hans Weishaupt

This study identifies somatic mutations in ALS genes in the motor cortex of sporadic ALS patients, particularly in excitatory neurons, suggesting a role in disease initiation.

bioRxiv · Mar 31, 2025 · PreprintGenetics