Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity
Bart R. Thomson, Henning Richter, Kevin Akeret, Raphael M. Buzzi, Vania Anagnostakou, Christiaan Hendrik Bas van Niftrik, Nina Schwendinger, Zsolt Kulcsár, Peter Kronen, Luca Regli, Jorn Fierstra, Dominik J. Schaer, Michael Hugelshofer
This study assesses the toxic effects of CSF-hemoglobin on cerebral blood flow and autoregulation using BOLD-CVR imaging and tests the protective role of haptoglobin in a sheep model.
Journal of Stroke and Cerebrovascular Diseases · Jan 12, 2023Peer-reviewedNeuroscience