Author

Nadja Schulthess-Lutz

University of ZurichORCID 0000-0002-2918-6262Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Dominik J. SchaeriD· 2 shared Florence VallelianiD· 2 shared Kerstin Hansen· 2 shared Livio BaselgiaiD· 2 shared Bart R. ThomsoniD· 1 shared Jan KlohsiD· 1 shared Kahrisan Kunasingam· 1 shared Kevin AkeretiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Dominik J. SchaerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A stress-NRF2 response axis polarises tumor macrophages and undermines immunotherapy

Dominik J. Schaer, Nadja Schulthess-Lutz, Livio Baselgia, Kahrisan Kunasingam, Rok Humar, Kerstin Hansen, Florence Vallelian

This study identifies NRF2 as a stress-response axis that polarizes tumor macrophages into immunosuppressive, therapy-resistant states, and shows that inhibiting NRF2 can restore immunotherapy efficacy.

bioRxiv · Jul 2, 2025 · PreprintImmunology

MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and edema in intracerebral hemorrhage

Kevin Akeret, Raphael M. Buzzi, Bart R. Thomson, Nina Schwendinger, Jan Klohs, Nadja Schulthess-Lutz, Livio Baselgia, Kerstin Hansen, Luca Regli, Florence Vallelian, Michael Hugelshofer, Dominik J. Schaer

This study identifies a biphasic inflammatory response after intracerebral hemorrhage, with an early MyD88-TLR4-dependent activation of the choroid plexus preceding secondary inflammation and leukocyte infiltration.

bioRxiv · Sep 6, 2022 · PreprintNeuroscience