Author

Nithya Sivaram

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Adrianus W.M. van der Velden· 1 shared Chen Liu· 1 shared Han V. Han· 1 shared Kien Pham· 1 shared Lisa M. Ballou· 1 shared Oleksi Petrenko· 1 shared Patrick A. McLaughlin· 1 shared Richard Z. LiniD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Adrianus W.M. van der Velden

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJan 15, 2019

PIK3CA in KrasG12D/Trp53R172H Tumor Cells Promotes Immune Evasion by Limiting Infiltration of T Cells in a Model of Pancreatic Cancer

Nithya Sivaram, Patrick A. McLaughlin, Han V. Han…·Richard Z. Lin

This study shows that PIK3CA-AKT signaling in pancreatic cancer cells limits T cell infiltration and tumor clearance by reducing MHC Class I and CD80 expression, suggesting it as a target for immunotherapy.

DOI 10.1101/521831

mouseexperimental assay

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