Autoinducer-2 functions as both a quorum sensing and metabolic signal in Escherichia coli
Noémie Godrie, Xuanlin Chen, Nicolas C Näpflin, Lukas Malfertheiner, Assa Yeroslaviz, Christopher Schubert, Rin Ho Kim, Christian von Mering, Leanid Laganenka
This study shows AI-2 functions as both a quorum sensing and metabolic signal in E. coli, linking nutrient sensing to population-level signaling through CRP and the lsr operon.
Applied and Environmental Microbiology · Oct 5, 2026Peer-reviewedMicrobiology