Christopher Schubert

This study shows AI-2 functions as both a quorum sensing and metabolic signal in E. coli, linking nutrient sensing to population-level signaling through CRP and the lsr operon.

The paper evaluates WISH-barcoding in Salmonella Typhimurium for in vivo population dynamics, finding wild-type strains prone to fitness-altering mutations during in vitro construction.

This study identifies D-gluconate as a key nutrient source for Salmonella during both acute and chronic infection, supporting its growth in the inflamed gut.

The paper shows that the gfr operon in Salmonella Typhimurium provides a fitness advantage during gut colonization by utilizing dietary Amadori compounds like fructoselysine.

The paper analyzes the pan-genome of nearly 20,000 Enterobacteriaceae genomes to identify core and accessory metabolic genes, revealing core genes for mixed acid fermentation and accessory genes for anaerobic respiration and carbohydrate utilization.

The paper shows that specific E. coli strains reduce Salmonella colonization by utilizing galactose, offering insights for microbiota-based infection control strategies.

This study investigates how AI-2 signaling and chemotaxis in E. coli influence its competitive interaction with Salmonella Typhimurium in the gut, affecting colonization resistance and metabolism.

This study identifies context-dependent and -independent carbohydrates used by Salmonella Typhimurium for gut colonization in mice, highlighting D-glucose, D-fructose, and D-galactose as key substrates.