Lukas Malfertheiner

Autoinducer-2 functions as both a quorum sensing and metabolic signal in Escherichia coli

This study shows AI-2 functions as both a quorum sensing and metabolic signal in E. coli, linking nutrient sensing to population-level signaling through CRP and the lsr operon.

The MicrobeAtlas database: Global trends and insights into Earth's microbial ecosystems

MicrobeAtlas unifies over two million microbiome samples to enable cross-technology insights into microbial ecosystems and their global patterns.

Community conservatism is widespread throughout microbial phyla and environments

The paper investigates community conservatism in microorganisms, finding it普遍存在 across environments and phyla, with specialized taxa showing stronger signals.

Enhanced semantic classification of microbiome sample origins using Large Language Models (LLMs)

This paper uses large language models to automate the annotation of microbiome sequencing records, achieving better performance than a keyword-based approach.

Unravelling the Core and Accessory Genome Diversity of Enterobacteriaceae in Carbon Metabolism

The paper analyzes the pan-genome of nearly 20,000 Enterobacteriaceae genomes to identify core and accessory metabolic genes, revealing core genes for mixed acid fermentation and accessory genes for anaerobic respiration and carbohydrate utilization.

Microbiome variations in osteoarthritis reflect aging and metabolic factors, not the disease

This study analyzes microbiome data from multiple OA cohorts and finds no significant differences between OA patients and controls, attributing microbiome changes to age and BMI instead of OA.

Habitat filtering but not microbiota origin controls microbiome transplant outcomes in soil

The paper investigates how microbiota origin affects transplant outcomes in soil, finding that habitat filtering, not origin, determines success.

Discovery of Theta Ribozymes in Gut Phages-Implications for tRNA and Alternative Genetic Coding

The paper identifies theta ribozymes in gut phages that associate with suppressor tRNAs, suggesting a role in regulating phage assembly through RNA-based mechanisms.