Leanid Laganenka

Development of a stable microbial community for the study of plasmid-mediated antimicrobial resistance in a continuous culturing device

This study develops a microbial community to study plasmid-mediated AMR spread, showing plasmids protect the community from antibiotics and that HGT dynamics can be controlled.

Autoinducer-2 functions as both a quorum sensing and metabolic signal in Escherichia coli

This study shows AI-2 functions as both a quorum sensing and metabolic signal in E. coli, linking nutrient sensing to population-level signaling through CRP and the lsr operon.

Emergent spatial structure in the gut microbiota is driven by bacterial growth and gut contractions

The paper shows how spatial structure in the gut microbiota emerges through bacterial growth in the matrix of gut content.

The Gfr uptake system provides a context-dependent fitness advantage to Salmonella Typhimurium SL1344 during the initial gut colonization phase

The paper shows that the gfr operon in Salmonella Typhimurium provides a fitness advantage during gut colonization by utilizing dietary Amadori compounds like fructoselysine.

Strain-specific galactose utilization by commensal E. coli mitigates Salmonella establishment in the gut

The paper shows that specific E. coli strains reduce Salmonella colonization by utilizing galactose, offering insights for microbiota-based infection control strategies.

Interplay between chemotaxis, quorum sensing, and metabolism regulates Escherichia coli-Salmonella Typhimurium interactions in vivo

This study investigates how AI-2 signaling and chemotaxis in E. coli influence its competitive interaction with Salmonella Typhimurium in the gut, affecting colonization resistance and metabolism.