Arsenite methyltransferase 3 regulates hepatic energy metabolism which dictates the hepatic response to arsenic exposure
Patrice Delaney, Nouf Khan, Matthew John O’Connor, Elizabeth Mayela Ambrosio, Anna Garcia‐Sabaté, Jeremy C. M. Teo, Spiros A. Pergantis, Elke Annette Ober, Kirsten C. Sadler
This paper shows that As3mt regulates hepatic energy metabolism independently of arsenic detoxification, leading to mitochondrial dysfunction and fatty liver in zebrafish mutants.
bioRxiv · Apr 5, 2023 · PreprintGenetics