Author

Elke Annette Ober

University of CopenhagenORCID 0000-0002-5195-1012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:zebrafish· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Iris A. UnterwegeriD· 2 shared Akvilė GasiūnaitėiD· 1 shared Ala TrusinaiD· 1 shared Alexandre E. Vanoosthuyse· 1 shared Anna Garcia‐SabatéiD· 1 shared Édouard HannezoiD· 1 shared Elizabeth Mayela AmbrosioiD· 1 shared Francesco CutraleiD· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersDevelopmental Biology

Iris A. UnterwegerORCID

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3 papers

Recent·Most cited

Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics

Iris A. Unterweger, Julie Klepstad, Édouard Hannezo, Pia R. Lundegaard, Ala Trusina, Elke Annette Ober

The paper uses lineage tracing and mathematical modeling in zebrafish to show that heterogeneous progenitor decisions establish a precise BEC-to-hepatocyte ratio and drive postembryonic liver growth.

PLoS Biology · Oct 4, 2023Peer-reviewedDevelopmental Biology

Arsenite methyltransferase 3 regulates hepatic energy metabolism which dictates the hepatic response to arsenic exposure

Patrice Delaney, Nouf Khan, Matthew John O’Connor, Elizabeth Mayela Ambrosio, Anna Garcia‐Sabaté, Jeremy C. M. Teo, Spiros A. Pergantis, Elke Annette Ober, Kirsten C. Sadler

This paper shows that As3mt regulates hepatic energy metabolism independently of arsenic detoxification, leading to mitochondrial dysfunction and fatty liver in zebrafish mutants.

bioRxiv · Apr 5, 2023 · PreprintGenetics

FRaeppli, a multispectral imaging toolbox for cell tracing and dense tissue analysis in zebrafish

Sara Caviglia, Iris A. Unterweger, Akvilė Gasiūnaitė, Alexandre E. Vanoosthuyse, Francesco Cutrale, Le A. Trinh, Scott E. Fraser, Stephan C. F. Neuhauss, Elke Annette Ober

FRaeppli enables multispectral imaging for cell tracing and tissue analysis in zebrafish, revealing new canalicular topologies in hepatocytes.

bioRxiv · Jan 14, 2022 · PreprintDevelopmental Biology