Human Histone Fragments Display Antibacterial Properties against Pseudomonas aeruginosa
Nourice Jaber, Angela Di Somma, Armando A. Rodriguez-alfonso, Carolina Canè, Clarissa Read, Ludger Ständker, Sebastian Wiese, Angela Duilio, Jan Münch, Barbara Spellerberg
This study identifies human histone H1.2 peptide as an antimicrobial agent against Pseudomonas aeruginosa, showing dose- and pH-dependent growth inhibition without cytotoxicity to mammalian cells.
Frontiers in Immunology · Aug 12, 2026Peer-reviewedMicrobiology