Reduced RNA turnover as a driver of cellular senescence
Nowsheen Mullani, Yevheniia Porozhan, Adèle Mangelinck, Christophe Rachez, Mickaël Costallat, Éric Batsché, Michèle Goodhardt, Giovanni Cenci, Carl Mann, Christian Muchardt
The paper shows that RNA accumulation, driven by reduced RNA turnover and oxidative stress, contributes to the inflammatory state of senescent cells.
Life Science Alliance · Jan 14, 2021Peer-reviewedMolecular Biology