Author

O. Akbulut

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

M. Cetin· 2 shared O. Saatci· 2 shared O. Sahin· 2 shared A. Uner· 1 shared B. Caliskan· 1 shared E. Banoglu· 1 shared K. Ibis· 1 shared M. Aras· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

M. Cetin

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer

M. E. Gedik, O. Saatci, N. Oberholtzer, M. Uner, O. Akbulut, M. Cetin, M. Aras, K. Ibis, B. Caliskan, E. Banoglu, S. Wiemann, A. Uner, S. Aksoy, S. Mehrotra, O. Sahin

This study shows that T-DM1 induces immunogenic cell death (ICD) in HER2-positive breast cancer, which is lost in resistance, and that targeting TACC3 restores ICD and enhances T-DM1 response.

bioRxiv · Sep 12, 2023 · PreprintCancer Biology

Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification

O. Saatci, O. Akbulut, M. Cetin, V. Sikirzhytski, O. Sahin

This study identifies TACC3 as a therapeutic target in breast cancers with centrosome amplification, showing its inhibition leads to apoptosis and growth suppression in organoids and xenografts.

bioRxiv · May 18, 2022Cancer Biology