Author

O. EL FAR

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Organism:rat· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

C. LEVEQUE· 2 shared F. YOUSSOUF· 2 shared M. SANGIARDI· 2 shared M. SEAGAR· 2 shared C. IBORRA· 1 shared F. Azzaz· 1 shared G. Ferracci· 1 shared J. Fantini· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCell Biology

C. LEVEQUE

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

A role for the V0 sector of the V-ATPase in neuroexocytosis: exogenous V0d blocks complexin and SNARE interactions with V0c

C. LEVEQUE, Y. MAULET, Q. WANG, M. RAME, S. MOCHIDA, M. SANGIARDI, F. YOUSSOUF, C. IBORRA, M. SEAGAR, N. VITALE, O. EL FAR

The paper shows that V0d inhibits V0c interactions with complexin and SNAREs, reducing neurotransmission in neurons.

bioRxiv · Jan 31, 2023 · PreprintCell Biology

Molecular landscape of BoNT/B bound to a membrane-inserted synaptotagmin/ganglioside complex

J. Ramirez-Franco, F. Azzaz, M. Sangiardi, G. Ferracci, F. Youssouf, M. R. Popoff, M. Seagar, C. Leveque, J. Fantini, O. EL FAR

This study presents a model of BoNT/B binding to a synaptotagmin/ganglioside complex in a membrane topology, revealing interactions and reduced sensitivity in Felidae with a synaptotagmin2 variant.

bioRxiv · Oct 18, 2021 · PreprintPharmacology & Toxicology