Author

N. Vitale

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:electrophysiology· 2 Research Focus:synaptic & neural circuits· 2

Frequent Co-Authors

S. Gasman· 3 shared S. Ory· 3 shared M. RAME· 2 shared P. Toth· 2 shared A. Blangy· 1 shared A. C. Pippione· 1 shared A. Cignetti· 1 shared A. Foudeh· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersCell Biology

S. Gasman

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Phospholipid Scramblase-1 is required for efficient neurotransmission and synaptic vesicle retrieval at cerebellar synapses

M. Caputo, D. Ivanova, S. Chasserot Golaz, F. Doussau, H. Anne Marie, S. Ozkan, J. Ecard, M. F. Bader, N. Vitale, M. A. Cousin, P. Toth, S. Gasman, S. Ory

This study shows that PLSCR1 is essential for synaptic vesicle retrieval and neurotransmission by regulating phospholipid asymmetry at cerebellar synapses.

bioRxiv · Oct 14, 2023 · PreprintCell Biology

A role for the V0 sector of the V-ATPase in neuroexocytosis: exogenous V0d blocks complexin and SNARE interactions with V0c

C. LEVEQUE, Y. MAULET, Q. WANG, M. RAME, S. MOCHIDA, M. SANGIARDI, F. YOUSSOUF, C. IBORRA, M. SEAGAR, N. VITALE, O. EL FAR

The paper shows that V0d inhibits V0c interactions with complexin and SNAREs, reducing neurotransmission in neurons.

bioRxiv · Jan 31, 2023 · PreprintCell Biology

ORP5 AND ORP8 ORCHESTRATE LIPID DROPLET BIOGENESIS AND MAINTENANCE AT ER-MITOCHONDRIA CONTACT SITES

V. Guyard, V. F. Monteiro-Cardoso, M. Omrane, C. Sauvanet, A. Houcine, C. Boulogne, K. B. MBarek, N. Vitale, O. Facklaris, N. El Khallouki, A. R. Thiam, F. Giordano

This study identifies ORP5 and ORP8 as regulators of lipid droplet biogenesis at ER-mitochondria contact sites by controlling seipin recruitment and phosphatidic acid enrichment.

bioRxiv · Nov 11, 2021Cell Biology

Dysfunction of exocytosis causes catecholamine hypersecretion in patient with pheochromocytoma

S. Houy, L. Streit, I. Drissa, M. Rame, C. Decraene, S. Moog, L. Brunaud, J. Lanoix, R. Chelbi, F. Bihain, S. Lacomme, S. Lomazzi, M. Vix, D. Mutter, E. Paramithiotis, , S. Gasman

The paper measures catecholamine secretion and exocytic protein expression in pheochromocytoma cells to show dysfunction in calcium-regulated exocytosis leads to hypersecretion.

bioRxiv · Nov 2, 2021 · PreprintCancer Biology

Design considerations of a wearable electronic-skin for mental health and wellness: balancing biosignals and human factors

Y. Khan, M. L. Mauriello, P. Nowruzi, A. Motani, G. Hon, N. Vitale, J. Li, J. Kim, A. Foudeh, D. Duvio, E. Shols, M. Chesnut, J. Landay, J. Liphardt, L. Williams, , P. E. Paredes

The paper designs a wearable electronic-skin for mental health monitoring, finding that upper arm and forearm are optimal wear locations by balancing human factors and biosignal accuracy.

bioRxiv · Jan 20, 2021 · PreprintBioengineering

The Synergism Between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid Leukemia

V. Gaidano, M. Houshmand, N. Vitale, G. Carra, A. Morotti, V. Tenace, S. Rapelli, S. Sainas, A. C. Pippione, M. Giorgis, D. Boschi, M. L. Lolli, A. Cignetti, G. Saglio, P. Circosta

This study shows that combining a DHODH inhibitor with dipyridamole induces metabolic lethality and apoptosis in AML cells, overcoming pyrimidine salvage pathway resistance.

bioRxiv · Oct 10, 2020Cancer Biology

Parkin coordinates mitochondrial lipid remodeling to execute mitophagy

C.-C. Lin, J. Yan, M. D. Kapur, K. L. Norris, C.-W. Hsieh, C.-H. Lai, N. Vitale, K.-L. Lim, Z. Guan, J.-T. Chi, W.-Y. Yang, T.-P. Yao

This study shows Parkin orchestrates mitochondrial lipid remodeling through phospholipase D2 and Lipin-1 to drive mitophagy via DAG production and autophagosome formation.

bioRxiv · Feb 28, 2020Cell Biology

The atypical Rho GTPase RhoU interacts with Intersectin-2 to regulate endosomal recycling pathways

O. Gubar, P. Croise, S. Kropyvko, T. Gryaznova, P. Toth, A. Blangy, N. Vitale, A. Rynditch, S. Gasman, S. Ory

This study identifies RhoU's interaction with Intersectin-2 to regulate endosomal recycling pathways through vesicle trafficking experiments.

bioRxiv · May 8, 2019Cell Biology