Author
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2 papers
Recent·Most cited
M. Potnis, J. Do, O. El Naggar, E. Noguchi, C. Sell
This study identifies the lncRNA H19/Let7b/EZH2 axis as a regulator of somatic cell senescence, showing H19 depletion leads to premature senescence and its role in modulating EZH2 levels.
bioRxiv · Jul 7, 2022 · PreprintCell Biology
G. Romano, F. Paradiso, P. Li, P. Shukla, L. N. Barger, O. El Naggar, J. P. Miller, R. J. Liang, T. L. Helms, A. J. Lazar, J. A. Wargo, F. Taraballi, J. C. Costello, L. N. Kwong
The paper shows that delivering Cxcl9 via microparticles enhances the effectiveness of BRAF inhibitors in melanoma by reducing minimal residual disease relapse.
bioRxiv · May 24, 2022Cancer Biology