Differential modulation of cellular phenotype and drug sensitivity by extracellular matrix proteins in primary and metastatic pancreatic cancer cells
O. H. Usman, S. Kumar, R. R. Walker, G. Xie, H. Sumajit, A. R. Jalil, S. Ramakrishnan, L. J. Dooling, Y. J. Wang, J. Irianto
This study shows that ECM proteins differentially affect morphology, proliferation, and drug sensitivity in primary but not metastatic pancreatic cancer cells, with transcriptomic changes in primary cells.
Molecular Biology of the Cell · Dec 1, 2023Peer-reviewedCancer Biology