Author

O. Kudlacek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

H. H. Sitte· 2 shared T. Stockner· 2 shared A. S. Alberto-Silva· 1 shared B. Khanppnavar· 1 shared C. Qi· 1 shared D. Luethi· 1 shared E. Bossi· 1 shared E. Lazzarin· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPharmacology & Toxicology

H. H. Sitte

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Bioisosteric analogs of MDMA with improved pharmacological profile

A. S. Alberto-Silva, S. Hemmer, H. A. Bock, L. Alves da Silva, K. R. Scott, N. Kastner, M. Bhatt, M. Niello, K. Jantsch, O. Kudlacek, E. Bossi, T. Stockner, M. R. Meyer, J. D. McCorvy, S. D. Brandt, , H. H. Sitte

This study evaluates three MDMA bioisosteres for improved pharmacological profiles, finding reduced off-target receptor activity and altered hepatic metabolism compared to MDMA.

bioRxiv · Apr 8, 2024 · PreprintPharmacology & Toxicology

Structural basis of organic cation transporter-3 inhibition

B. Khanppnavar, J. Maier, F. Herborg, R. Gradisch, E. Lazzarin, D. Luethi, J.-W. Yang, C. Qi, M. Holy, K. Jaentsch, O. Kudlacek, K. Schicker, T. Werge, U. Gether, T. Stockner, , H. H. Sitte

The paper determines the cryo-EM structure of OCT3 and analyzes genetic variants to understand its function and inhibition.

bioRxiv · Jul 14, 2022Pharmacology & Toxicology