Author

T. Stockner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

H. H. Sitte· 2 shared O. Kudlacek· 2 shared A. S. Alberto-Silva· 1 shared A. Schamberger· 1 shared B. Khanppnavar· 1 shared C. Qi· 1 shared D. Luethi· 1 shared E. Bossi· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersPharmacology & Toxicology

H. H. Sitte

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Bioisosteric analogs of MDMA with improved pharmacological profile

A. S. Alberto-Silva, S. Hemmer, H. A. Bock, L. Alves da Silva, K. R. Scott, N. Kastner, M. Bhatt, M. Niello, K. Jantsch, O. Kudlacek, E. Bossi, T. Stockner, M. R. Meyer, J. D. McCorvy, S. D. Brandt, , H. H. Sitte

This study evaluates three MDMA bioisosteres for improved pharmacological profiles, finding reduced off-target receptor activity and altered hepatic metabolism compared to MDMA.

bioRxiv · Apr 8, 2024 · PreprintPharmacology & Toxicology

Nucleotide binding is the critical regulator of ABCG2 conformational transitions

Z. Gyöngy, G. Mocsar, E. Hegedus, T. Stockner, Z. Ritter, L. Homolya, A. Schamberger, T. I. Orban, J. Remenyik, G. Szakacs, K. Goda

This study investigates how nucleotide binding regulates conformational transitions in ABCG2, showing it induces the inward-to-outward facing switch and interacts with substrate binding.

bioRxiv · Oct 19, 2022Biochemistry

Structural basis of organic cation transporter-3 inhibition

B. Khanppnavar, J. Maier, F. Herborg, R. Gradisch, E. Lazzarin, D. Luethi, J.-W. Yang, C. Qi, M. Holy, K. Jaentsch, O. Kudlacek, K. Schicker, T. Werge, U. Gether, T. Stockner, , H. H. Sitte

The paper determines the cryo-EM structure of OCT3 and analyzes genetic variants to understand its function and inhibition.

bioRxiv · Jul 14, 2022Pharmacology & Toxicology