Ambient Temperature Bacterial Large Ribosomal Subunit Structure Enabled by Serial Femtosecond X-ray Crystallography
B. Tosun, Y. Rao, E. Destan, E. H. Dao, F. B. Ertem, M. Yilmaz, I. Yapici, M. Gul, E. Ayan, J. A. Johnson, A. Shafiei, C. Kulakman, B. Hayes, M. Liang, C. H. Yoon, , H. DeMirci
This study determines the structure of the 50S ribosomal subunit from Thermus thermophilus at ambient temperature using serial femtosecond X-ray crystallography, revealing new dynamics and antibiotic binding sites.
bioRxiv · Oct 24, 2023 · PreprintBiophysics