Author

B. Tosun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein structure prediction· 4 Assay:structural biology· 3 Assay:protein structure· 2 Organism:bacteria (other)· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. A. Johnson· 5 shared C. Kulakman· 4 shared E. Ayan· 4 shared E. Destan· 4 shared F. B. Ertem· 4 shared H. DeMirci· 4 shared I. Yapici· 4 shared M. Yilmaz· 4 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersBiophysics

J. A. Johnson

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5 papers

Recent·Most cited

4D Crystallography Captures Transient IF1-Ribosome Dynamics in Translation Initiation

I. Yapici, E. H. Dao, S. Yokoi, E. Destan, E. Ayan, A. Shafiei Kamel, F. B. Ertem, C. Kulakman, M. Yilmaz, B. Tosun, H. Ciftci, A. Kepceoglu, J. A. Johnson, O. Guven, A. Ergul, , H. DeMirci

This study uses 4D crystallography to capture transient dynamics of IF1 binding to the 30S ribosomal subunit, revealing allostery and interactions during translation initiation.

bioRxiv · Oct 27, 2023 · PreprintBiophysics

Ambient Temperature Bacterial Large Ribosomal Subunit Structure Enabled by Serial Femtosecond X-ray Crystallography

B. Tosun, Y. Rao, E. Destan, E. H. Dao, F. B. Ertem, M. Yilmaz, I. Yapici, M. Gul, E. Ayan, J. A. Johnson, A. Shafiei, C. Kulakman, B. Hayes, M. Liang, C. H. Yoon, , H. DeMirci

This study determines the structure of the 50S ribosomal subunit from Thermus thermophilus at ambient temperature using serial femtosecond X-ray crystallography, revealing new dynamics and antibiotic binding sites.

bioRxiv · Oct 24, 2023 · PreprintBiophysics

Crystal Structure of the 4-Hydroxybutyryl-CoA Synthetase (ADP-forming) from Nitrosopumilus maritimus

J. A. Johnson, B. B. Tolar, B. Tosun, Y. Yoshikuni, C. A. Francis, S. Wakatsuki, H. Demirci

The paper presents the crystal structure of Nmar_0206 from Nitrosopumilus maritimus, revealing a conserved interdomain linker loop that influences homodimer stability and contributes to the enzyme's energy efficiency in the 3HP/4HB cycle.

bioRxiv · Jul 14, 2023Biophysics

Rapid and Efficient Ambient Temperature X-ray Crystal Structure Determination at Turkish Light Source

M. Gul, E. Ayan, E. Destan, J. A. Johnson, A. Shafiei, A. Kepceoglu, M. Yilmaz, F. B. Ertem, I. Yapici, B. Tosun, N. Baldir, N. Tokay, Z. Nergiz, G. Karakadioglu, S. S. Paydos, , H. DeMirci

The paper introduces a plate-reader module for rapid ambient temperature X-ray crystallography at a home source and reports the first lysozyme structure determined at Turkish DeLight.

bioRxiv · Oct 12, 2022 · PreprintBiophysics

Cryogenic X-ray crystallographic studies of biomacromolecules at Turkish Light Source: Turkish DeLight

N. Atalay, E. K. Akcan, M. Gul, E. Ayan, E. Destan, F. B. Ertem, N. Tokay, B. Cakilkaya, Z. Nergiz, G. Karakadioglu, A. Kepceoglu, I. Yapici, B. Tosun, N. Baldir, G. Yildirim, , Kati

The paper describes the setup and application of a new X-ray crystallography facility in Turkey for structural analysis of biomacromolecules using lysozyme as a model.

bioRxiv · Sep 3, 2022Biophysics