Ebola virus requires phosphatidylserine scrambling activity for efficient budding and optimal infectivity
M. D. Acciani, M. F. Lay-Mendoza, K. E. Havranek, O. L. Linn, A. M. Duncan, H. Iyer, M. A. Brindley
This study shows that XKR8, not TMEM16F, is essential for Ebola virus budding and infectivity by enabling phosphatidylserine (PS) externalization on the viral envelope.
bioRxiv · Mar 16, 2020Microbiology