Regulation of oxidative phosphorylation by Nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice
T. Venit, O. Sapkota, W. S. Abdrabou, P. Loganathan, R. Pasricha, S. R. Mahmood, N. El Said, S. Thomas, Y. Idaghdour, M. Magzoub, P. Percipalle
This study shows that nuclear myosin 1 regulates oxidative phosphorylation and prevents metabolic reprogramming and tumorigenesis in mice by modulating mitochondrial function and the PI3K/Akt/mTOR pathway.
bioRxiv · Jun 30, 2022 · PreprintCell Biology