Computational reconstruction of the complete Piezo1 structure reveals a unique footprint and specific lipid interactions
J. Chong, D. De Vecchis, A. J. Hyman, O. V. Povstyan, J. Shi, D. J. Beech, A. C. Kalli
This study computationally reconstructs the full-length Piezo1 structure, revealing its trilobed topology, lipid interactions, and how membrane stiffness affects its shape.
bioRxiv · Sep 26, 2019Biophysics