Cancer BiologybioRxiv
Chemical, physical and biological triggers of Bcl-xL-mediated apoptosis
A. Ianevski, E. Kulesskiy, K. Krpina…·D. E. Kainov
This study shows that Bcl-xL-specific inhibitors, when combined with DNA-damaging agents or physical insults, trigger apoptosis in various cell types and C. elegans by releasing Bad and Bax from Bcl-xL.
DOI 10.3390/cancers12061694