Human genomic DNA is widely interspersed with i-motif structures
Cristian David Peña Martinez, Mahdi Zeraati, Romain Rouet, Ohan Mazigi, Jake Y. Henry, Brian Gloss, Jessica A. Kretzmann, Cameron W. Evans, Emanuela Ruggiero, Irene Zanin, Maja Marušič, Janez Plavec, Sara N. Richter, Tracy M. Bryan, Nicole M. Smith, , Daniel Christ
The paper identifies over 650,000 i-motif structures in human genomic DNA using immunoprecipitation and sequencing, showing their widespread distribution and association with highly expressed genes and G0/G1 phase upregulated genes.
The EMBO Journal · Aug 29, 2024Peer-reviewedGenetics