Author

Nicole M. Smith

The University of Western AustraliaORCID 0000-0002-5519-8152Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Cameron W. EvansiD· 2 shared Alka SaxenaiD· 1 shared Brian GlossiD· 1 shared Clémentine Mercé· 1 shared Cristian David Peña MartineziD· 1 shared Daniel ChristiD· 1 shared Emanuela RuggieroiD· 1 shared Erik W. ThompsoniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetics

Cameron W. EvansORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Human genomic DNA is widely interspersed with i-motif structures

Cristian David Peña Martinez, Mahdi Zeraati, Romain Rouet, Ohan Mazigi, Jake Y. Henry, Brian Gloss, Jessica A. Kretzmann, Cameron W. Evans, Emanuela Ruggiero, Irene Zanin, Maja Marušič, Janez Plavec, Sara N. Richter, Tracy M. Bryan, Nicole M. Smith, , Daniel Christ

The paper identifies over 650,000 i-motif structures in human genomic DNA using immunoprecipitation and sequencing, showing their widespread distribution and association with highly expressed genes and G0/G1 phase upregulated genes.

The EMBO Journal · Aug 29, 2024Peer-reviewedGenetics

Metastable Intermediates Identified in Epithelial to Mesenchymal Transition are Regulated by G-Quadruplex DNA Structures

Jessica J. King, Cameron W. Evans, Ulrich D. Kadolsky, Marck Nörret, Muhammad Munir Iqbal, Clémentine Mercé, Sugandha Bhatia, Philip A. Gregory, Erik W. Thompson, Alka Saxena, K. Swaminathan Iyer, Nicole M. Smith

The paper introduces a new multiplexed single-cell sequencing method to identify metastable cell states during EMT and shows G-quadruplex DNA stabilization can inhibit EMT.

bioRxiv · Aug 21, 2023 · PreprintGenomics