Sara N. Richter

HTLV-1 antisense transcription is promoted by increased SP1 binding at 3'-LTR G-Quadruplexes

The paper identifies G-quadruplex structures in HTLV-1 3'-LTR and shows they enhance antisense transcription via SP1 binding.

The iMab antibody selectively binds to intramolecular and intermolecular i-motif structures

The paper investigates the selectivity of the iMab antibody for i-motif structures, showing it binds both intramolecular and intermolecular iMs, and highlights the impact of experimental conditions on binding.

Human genomic DNA is widely interspersed with i-motif structures

The paper identifies over 650,000 i-motif structures in human genomic DNA using immunoprecipitation and sequencing, showing their widespread distribution and association with highly expressed genes and G0/G1 phase upregulated genes.

Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

The paper shows that promoter G-quadruplexes and transcription factors like AP-1 and SP1 work together to regulate cell-specific gene expression in liposarcoma and keratinocytes.

G-quadruplex forming sequences in the genome of all known human viruses: a comprehensive guide

The paper identifies and classifies G-quadruplex forming sequences in the genomes of all known human viruses, showing they can be used to classify viruses into families.