Modeling pancreatic cancer tumor stroma co-evolution in an in ovo model
Raphela A. Ranjan, Aashreya Ravichandra, Philipp Putze, Anna Chernysheva, Johannes Wirth, Daniele Lucarelli, Wing Yin Ng, Oleksandra Pavlovska, Khanyile Sibusisiwe Sibanda, Erik Leipe, Felix Schicktanz, Stefanie Bärthel, Anna Melissa Schlitter, Rupert Öllinger, Marc Ringelhan, , Maximilian Reichert
This study uses an in ovo model to show that the CAM platform supports tumor-stroma coevolution in pancreatic cancer, preserving patient-specific features and enabling functional analysis of stromal interactions.
bioRxiv · Jun 27, 2026 · PreprintCancer Biology