Maximilian Reichert

This study uses an in ovo model to show that the CAM platform supports tumor-stroma coevolution in pancreatic cancer, preserving patient-specific features and enabling functional analysis of stromal interactions.

This study identifies c-Rel as a driver of pancreatic cancer metastasis by promoting EMT, ECM remodeling, and resistance to isolation stress through fibronectin-integrin signaling.

This study identifies ATR inhibitors as synergistic with gemcitabine in killing PDAC cells by blocking the DNA damage response pathway.

This study shows that pancreatic ductal adenocarcinoma cells in collagen droplets form branched organoids with complex morphology, suggesting accelerated maturation compared to traditional bulk culture.

This paper demonstrates the use of generative AI to design de novo binders for CAR-T cells targeting cancer antigens, showing comparable efficacy to traditional scFv-based CAR-T cells.