Genetic and environmental interactions outweigh mitonuclear coevolution for complex traits in Drosophila
Leah J. Darwin, Faye A. Lemieux, Rebecca Z. Bachtel, Jack H. Blocker, Camille P. Brown, Alexander D. Griffin, Jacob D. Lerman, Olivia C. Maule, Yevgeniy Raynes, David M. Rand
The paper quantifies the relative contributions of mitochondrial, nuclear, and environmental variation to complex traits in Drosophila, finding that genetic and environmental interactions outweigh mitonuclear coevolution.
bioRxiv · Nov 24, 2025 · PreprintEvolutionary Biology