Biogenesis and antigen presentation properties of dendritic cell-derived apoptotic bodies
Amy L. Hodge, Jascinta P. Santavanond, Bo Shi, Sarah Caruso, Sara Oveissi, Caitlin L. Vella, Omar Audi, Dilara Ceyda Ozkocak, Stephanie F. Rutter, Thanh Kha Phan, Lanzhou Jiang, Satoko Arakawa, Shigeomi Shimizu, Ikuyo Yoshino, Georgia K. Atkin‐Smith, , Ivan K. H. Poon
This study shows that apoptotic dendritic cells release large extracellular vesicles called apoptotic bodies that can directly present antigens and modulate immune responses.
bioRxiv · Jul 6, 2026 · PreprintCell Biology