Author

Jascinta P. Santavanond

La Trobe UniversityORCID 0000-0002-7950-6316Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Ivan K. H. PooniD· 3 shared Amy A. BaxteriD· 2 shared Amy L. Hodge· 2 shared Dilara Ceyda OzkocakiD· 2 shared Georgia K. Atkin‐SmithiD· 2 shared Ikuyo Yoshino· 2 shared Lanzhou JiangiD· 2 shared Mark D. HulettiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

Ivan K. H. PoonORCID

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Author profile →

3 papers

Recent·Most cited

Partitioning of nuclear material into apoptotic fragments through establishment of asymmetric cell death morphology

Jascinta P. Santavanond, Lanzhou Jiang, Amy L. Hodge, Dilara Ceyda Ozkocak, Alper Ceviker, Satoko Arakawa, Shigeomi Shimizu, Ikuyo Yoshino, Stephanie F. Rutter, Thanh Kha Phan, Rochelle Tixeira, Amy A. Baxter, Sarah Caruso, Lucas M. Newton, Rebecca K. Stephens, , Ivan K. H. Poon

This study identifies a new apoptotic morphology, AsyCDM, where apoptotic cells asymmetrically partition nuclear material into apoptotic bodies via ROCK1-dependent actomyosin contraction.

bioRxiv · Jul 14, 2026 · PreprintCell Biology

Biogenesis and antigen presentation properties of dendritic cell-derived apoptotic bodies

Amy L. Hodge, Jascinta P. Santavanond, Bo Shi, Sarah Caruso, Sara Oveissi, Caitlin L. Vella, Omar Audi, Dilara Ceyda Ozkocak, Stephanie F. Rutter, Thanh Kha Phan, Lanzhou Jiang, Satoko Arakawa, Shigeomi Shimizu, Ikuyo Yoshino, Georgia K. Atkin‐Smith, , Ivan K. H. Poon

This study shows that apoptotic dendritic cells release large extracellular vesicles called apoptotic bodies that can directly present antigens and modulate immune responses.

bioRxiv · Jul 6, 2026 · PreprintCell Biology

Novel naphthyridones targeting Pannexin 1 for colitis management

Wen‐Yun Hsueh, Yiling Wu, Meng‐Tzu Weng, Shin‐Yun Liu, Jascinta P. Santavanond, Yi‐Chung Liu, Ching‐I Lin, Cheng‐Nong Lai, Yi‐Ru Lu, Jing Yin Hsu, Hong‐Yu Gao, Jinq‐Chyi Lee, Shu‐Chen Wei, Pingchiang C. Lyu, Ivan K. H. Poon, , Yu‐Hsin Chiu

The paper identifies a novel naphthyridone inhibitor of PANX1 with reduced off-target effects, showing efficacy in a mouse model of IBD.

Advanced Science · Dec 30, 2024Peer-reviewedMolecular Biology