PathologybioRxivPreprint
Cognitive deficits found in a pro-inflammatory state are independent of ERK 1/2 signaling in the murine brain hippocampus treated with Shiga toxin 2 from enterohemorrhagic Escherichia Coli
C. Berdasco, A. Pinto, M. Blake…·J. Goldstein
This study shows that Stx2 induces cognitive deficits and inflammation in the hippocampus independently of ERK 1/2 signaling, while LPS requires ERK 1/2 for NF-kB activation.
DOI 10.1101/2020.08.24.264929