P. A. Randazzo

Point mutations in Arf1 reveal cooperative effects of the N-terminal region and myristate for GTPase-activating protein catalytic activity

The paper investigates how point mutations in Arf1 affect its interaction with GAPs, revealing cooperative effects between the N-terminal region and myristate on catalytic activity.

Fusion-negative rhabdomyosarcoma orthotopic tongue xenografts for study of invasion, intravasation and metastasis in live animals

CIB2 regulates autophagy via Rheb-mTORC1 signaling axis

This study identifies CIB2 as a regulator of autophagy in RPE cells through the Rheb-mTORC1 signaling pathway, linking it to AMD and mTORC1-related diseases.