Author

P. A. Weidenbacher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

P. S. Kim· 3 shared M. Sanyal· 2 shared A. E. Powell· 1 shared C. Hanson· 1 shared J. Do· 1 shared J. E. Pak· 1 shared K. Zhang· 1 shared M. K. Morris· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

P. S. Kim

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Decreased efficacy of a COVID-19 vaccine due to mutations present in early SARS-CoV-2 variants of concern

P. A. Weidenbacher, N. Friedland, M. Sanyal, M. K. Morris, J. Do, C. Hanson, P. S. Kim

This study evaluates the efficacy of a pan-sarbecovirus vaccine candidate against SARS-CoV-2 variants, finding that omitting strain-specific mutations improves cross-reactive neutralizing antibody responses.

bioRxiv · Jun 27, 2023 · PreprintBiochemistry

A single immunization with spike-functionalized ferritin vaccines elicits neutralizing antibody responses against SARS-CoV-2 in mice

A. E. Powell, K. Zhang, M. Sanyal, S. Tang, P. A. Weidenbacher, S. Li, T. D. Pham, J. E. Pak, W. Chiu, P. S. Kim

This study shows that a single dose of spike-functionalized ferritin vaccines in mice generates neutralizing antibodies against SARS-CoV-2, with S{Delta}C-Fer showing higher efficacy than other spike formats.

bioRxiv · Aug 28, 2020Immunology

Protect, Modify, Deprotect (PMD): A strategy for creating vaccines to elicit antibodies targeting a specific epitope

P. A. Weidenbacher, P. S. Kim

This paper introduces PMD, a method to create vaccines that direct antibody responses toward specific epitopes by protecting, modifying, and deprotecting antigens.

bioRxiv · Dec 28, 2018Immunology