Author

P. B. Sehgal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

H. Yuan· 3 shared F.-X. Liang· 2 shared Y. Deng· 2 shared A. Mackiewicz· 1 shared C. Petzold· 1 shared D. Davis· 1 shared J. Sall· 1 shared J. Westley· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCell Biology

H. Yuan

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3 papers

Recent·Most cited

Rapid reversible osmoregulation of cytoplasmic biomolecular condensates of human interferon-α-induced antiviral MxA GTPase

P. B. Sehgal, H. Yuan, Y. Jin

This study shows that MxA GTPase condensates rapidly disassemble and reassemble in response to osmotic changes, maintaining antiviral activity during hypoosmolar conditions.

bioRxiv · Aug 30, 2022Biochemistry

Murine GFP-Mx1 forms phase-separated nuclear condensates and associates with cytoplasmic intermediate filaments: novel antiviral activity against vesicular stomatitis virus

P. B. Sehgal, H. Yuan, M. F. Scott, Y. Deng, F.-X. Liang, A. Mackiewicz

bioRxiv · Aug 12, 2020Cell Biology

Human antiviral protein MxA forms novel metastable membrane-less cytoplasmic condensates exhibiting rapid reversible \"crowding\"-driven phase transitions

D. Davis, H. Yuan, F.-X. Liang, Y.-M. Yang, J. Westley, C. Petzold, K. Dancel-Manning, Y. Deng, J. Sall, P. B. Sehgal

This study shows that the human antiviral protein MxA forms metastable cytoplasmic condensates that undergo rapid reversible phase transitions in response to osmotic changes.

bioRxiv · Mar 5, 2019 · PreprintCell Biology