Author

P. B. Stathopulos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:electrophysiology· 1

Frequent Co-Authors

B. Domingo· 1 shared C. Ferec· 1 shared C. L. Pin· 1 shared C. Le Marechal· 1 shared E. Masson· 1 shared F. Antigny· 1 shared F. Campeotto· 1 shared J. Llopis· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

B. Domingo

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Author profile →

3 papers

Recent·Most cited

Defining the SPCA2C interactome identifies unique links to store-operated calcium entry

P. Samardzija, M. A. Fenech, R. Lang, M. C. Carter, S. Chen, S. Shi, P. B. Stathopulos, C. L. Pin

This study identifies novel SPCA2C interactors involved in calcium signaling and vesicular transport using BioID and validates key interactions with STIM1, ESYT1, and CCDC47.

bioRxiv · Sep 13, 2023 · PreprintCell Biology

p.E152K-STIM1 mutation deregulates Ca2+ signaling contributing to chronic pancreatitis.

M. Burgos, R. Phillipe, F. Antigny, P. Buscaglia, E. Masson, S. Mukherjee, P. Dubar, C. Le Marechal, F. Campeotto, N. Lebonvallet, M. Frieden, J. Llopis, B. Domingo, P. B. Stathopulos, M. Ikura, , O. Mignen

The paper identifies a p.E152K-STIM1 mutation that disrupts Ca2+ signaling in pancreatic acinar cells, leading to trypsin activation and cell death in pancreatitis patients.

bioRxiv · Jan 22, 2020Cell Biology

S-Nitrosylation of STIM1 by neuronal nitric oxide synthase inhibits store-operated Ca2+ entry

L. Gui, J. Zhu, X. Lu, S. M. Sims, W.-Y. Lu, P. B. Stathopulos, Q. Feng

This study shows that S-nitrosylation of STIM1 by nNOS inhibits SOCE in cardiomyocytes by stabilizing the luminal domain and preventing oligomerization.

bioRxiv · Apr 18, 2018Physiology