Author

R. Lang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:imaging· 1

Frequent Co-Authors

B. Bodendorfer· 2 shared A. Bozec· 1 shared A. Luhrmann· 1 shared A. Preikschat· 1 shared A. Schmidt· 1 shared C. Alexander· 1 shared C. Bogdan· 1 shared C. Daniel· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

B. Bodendorfer

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Defining the SPCA2C interactome identifies unique links to store-operated calcium entry

P. Samardzija, M. A. Fenech, R. Lang, M. C. Carter, S. Chen, S. Shi, P. B. Stathopulos, C. L. Pin

This study identifies novel SPCA2C interactors involved in calcium signaling and vesicular transport using BioID and validates key interactions with STIM1, ESYT1, and CCDC47.

bioRxiv · Sep 13, 2023 · PreprintCell Biology

Macrophages inhibit Coxiella burnetii by the ACOD1-itaconate pathway for containment of Q fever

L. Kohl, N. A. A. Siddique, B. Bodendorfer, R. Berger, A. Preikschat, C. Daniel, M. Oelke, M. Mauermeir, K.-T. Yang, I. Hayek, M. Szperlinski, J. Schulze-Luehrmann, U. Schleicher, A. Bozec, G. Kroenke, , R. Lang

This study identifies the ACOD1-itaconate pathway in macrophages as critical for restricting Coxiella burnetii replication and proposes it as a therapeutic target for Q fever.

bioRxiv · May 10, 2022Immunology

Preclinical establishment of a divalent vaccine against SARS-CoV-2

Z. Hevesi, D. Gerges, S. Kapps, R. Freire, S. Schmidt, D. Pollak, K. Schmetterer, T. Frey, R. Lang, W. Winnicki, A. Schmidt, T. Harkany, L. Wagner

This paper develops a divalent vaccine against SARS-CoV-2 that induces strong IgG responses and T-cell activation, showing durability and cross-variant protection.

bioRxiv · Feb 10, 2022Bioengineering

IL-4 and helminth infection downregulate MINCLE-dependent macrophage response to mycobacteria and Th17 adjuvanticity

R. Lang, S. Wirtz, D. Voehringer, M. Lacorcia, M. Altunay, B. Bodendorfer, C. Schubart, D. Christensen, C. Alexander, J. Schick, C. P. da Costa

This study shows IL-4 and helminth infection reduce MINCLE expression on macrophages, impairing Th17 responses to MINCLE-based vaccines.

bioRxiv · Aug 17, 2021Immunology

Virtual-SMLM, a virtual environment for real-time interactive SMLM acquisition

J. Griffie, T.-A. M. Pham, C. Sieben, R. Lang, V. Cevher, S. Holden, M. Unser, S. Manley, D. Sage

Virtual-SMLM provides a virtual environment for real-time interactive single molecule localisation microscopy acquisition, enabling training and validation of automated methods with realistic simulated data.

bioRxiv · Mar 5, 2020 · PreprintBiophysics