Author

P. Barker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

K. Burling· 2 shared A. P. Mander· 1 shared A. Smith· 1 shared A.-C. Prowald· 1 shared B. Lopez· 1 shared C. Guy· 1 shared D. B. Dunger· 1 shared F. Ackland· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPhysiology

K. Burling

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3 papers

Recent·Most cited

Fluorogenic, sub-single-turnover monitoring of enzymatic reactions involving NAD(P)H provides a generalised platform for directed ultrahigh throughput evolution of biocatalysts in microdroplets

M. Penner, O. J. Klein, M. Gantz, F. Nintzel, A.-C. Prowald, S. Boss, P. Barker, P. Dupree, F. Hollfelder

The paper develops a fluorogenic assay for NAD(P)H detection to enable high-throughput screening of biocatalysts in microdroplets, demonstrating improved sensitivity and applicability for glycosyl hydrolases and IREDs.

bioRxiv · Nov 22, 2023 · PreprintBiochemistry

A Wars2 mutant mouse shows a sex and diet specific change in fat distribution, reduced food intake and depot-specific upregulation of WAT browning

M. Muso, L. Bentley, L. Vizor, M. Yon, K. Burling, P. Barker, L. A. K. Zolkiewski, R. D. Cox, R. Dumbell

This study shows that Wars2V117L/V117L mice exhibit sex and diet-specific changes in fat distribution, reduced food intake, and depot-specific upregulation of WAT browning.

bioRxiv · May 23, 2022Physiology

Frequent Monitoring of C-peptide Levels in Newly Diagnosed Type 1 Subjects Using Dried Blood Spots Collected at Home

R. H. Willemsen, K. Burling, P. Barker, F. Ackland, R. P. Dias, J. Edge, A. Smith, J. Todd, B. Lopez, A. P. Mander, C. Guy, D. B. Dunger

This study evaluates a method for frequent C-peptide monitoring at home using dried blood spots in newly diagnosed type 1 diabetes patients, showing strong correlation with plasma levels and potential for tracking beta-cell function changes.

bioRxiv · Mar 21, 2018Biochemistry