PDZ and LIM domain protein 2 plays dual and context-dependent roles in breast cancer development
J. Maryas, J. Pribyl, P. Bouchalova, P. Skladal, P. Bouchal
This study shows PDLIM2 has opposing roles in breast cancer and normal cells, promoting EMT and metastasis in cancer cells while maintaining epithelial phenotype in normal cells.
bioRxiv · Jan 27, 2020 · PreprintCancer Biology