Author

P. C. Lin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. Hong· 4 shared T. R. Wuest· 3 shared Y. Min· 2 shared P. Qu· 1 shared S. Yanpallewar· 1 shared Y. Kim· 1 shared

Activity by Year

2019-2019 · peak 4/yr

Co-Author Collaboration Network

6 top collaborators · 8 mutual co-author links

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4 shared papersCell Biology

J. Hong

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The Rho/Rac guanine nucleotide exchange factor Vav1 regulates HIF-1α; and GLUT-1 expression and glucose uptake in the brain

J. Hong, Y. Kim, S. Yanpallewar, P. C. Lin

This study identifies Vav1's role in regulating HIF-1α and GLUT-1, showing that Vav1 deficiency reduces glucose uptake in the brain and impairs learning.

bioRxiv · Oct 16, 2019Cell Biology

Neutrophilic granule protein is a novel murine LPS antagonist

J. Hong, P. Qu, T. R. Wuest, P. C. Lin

The paper identifies NGP as a secreted murine protein that inhibits LPS function by blocking its interaction with TLR4.

bioRxiv · Aug 13, 2019Immunology

Oxygen tension regulates lysosomal activation and receptor tyrosine kinase degradation

J. Hong, T. R. Wuest, Y. Min, P. C. Lin

This study shows hypoxia suppresses lysosomal activation and RTK degradation, linking oxygen tension to lysosomal function and suggesting lysosomal activation as a therapeutic target in cancer.

bioRxiv · Aug 6, 2019Cell Biology

Vav1 is essential for HIF-1α activation in vascular response to ischemic stress

Y. Min, J. Hong, T. R. Wuest, P. C. Lin

This study shows Vav1 is essential for HIF-1α activation in vascular response to ischemic stress, revealing a regulatory mechanism similar to HIF-1.

bioRxiv · Aug 6, 2019Cancer Biology