The Rho/Rac guanine nucleotide exchange factor Vav1 regulates HIF-1α; and GLUT-1 expression and glucose uptake in the brain
J. Hong, Y. Kim, S. Yanpallewar, P. C. Lin
This study identifies Vav1's role in regulating HIF-1α and GLUT-1, showing that Vav1 deficiency reduces glucose uptake in the brain and impairs learning.
bioRxiv · Oct 16, 2019Cell Biology